Update: Availability of Rabies Vaccine and Immune Globulin

Indiana State Department of Health Logo

Indiana Health Alert Network Notification – November 26, 2019

Update: Availability of Rabies Vaccine and Immune Globulin

The Centers for Disease Control and Prevention (CDC) recently reported a limited or unavailable supply for both rabies vaccine and rabies immune globulin. Supply is currently limited for one rabies vaccine and one rabies immune globulin product. The current supply limitations are not expected to impact overall availability of rabies biologics nationally. Healthcare providers should continue to administer pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP) when indicated.

Availability of Human Rabies Vaccine

RabAvert rabies vaccine (produced by GlaxoSmithKline) is experiencing a temporary limited supply, but is still available for both PrEP and PEP. Clinicians can request RabAvert for any patient who needs PrEP or PEP by contacting GSK’s Vaccine Service Center directly at 866-475-8222, option 3. IMOVAX rabies vaccine (produced by Sanofi Pasteur) is now available, following a shortage earlier this year. Sanofi Pasteur began shipping IMOVAX on October 28, 2019. IMOVAX is available from wholesalers, distributors and directly from the manufacturer. Call Sanofi Pasteur at 1-800-VACCINE if IMOVAX is not available from your wholesalers or distributors.

Availability of Human Rabies Immune Globulin

KEDRAB (produced by Kedrion Biopharma) is available with no restrictions.

HyperRab (produced by Grifols) is available with no restrictions. (HyperRab is a more potent version of the previously licensed HyperRab S/D and requires a smaller volume to achieve the recommended 20 IU/kg dose.)

Imogam (produced by Sanofi Pasteur) is currently experiencing a temporary shortage and is only available to healthcare providers who have a patient with current suspected rabies exposure requiring immediate PEP. Providers can obtain Imogam directly from the manufacturer by faxing a completed Rabies Post-Exposure Form (found at vaccineshoppe.com) to 1-877-287-9391 (Attn: Sanofi Pasteur Customer Service).

For updates, please visit https://www.cdc.gov/rabies/resources/availability.html.

Read the full health alert here (PDF file).